Postdoctoral Scientist – Inner Ear Research & Cochlear Gene Therapy – Otolaryngology
Cedars-Sinai · Los Angeles, California
What the posting says
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- Employment typeStated
- Other
- EducationStated
- ['postgraduate degree']
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Requirements, each with its sentence from the posting
These are the employer’s words. The index does not judge whether you meet them.
- PhD, MD, MD/PhD, VMD, or equivalent doctoral degreerequired
PhD, MD, MD/PhD, VMD, or equivalent doctoral degree in a relevant field
from the posting - Mouse breeding and colony managementpreferred
Perform mouse breeding, colony management, husbandry, and experimental planning
from the posting - Cochlear surgeries and therapeutic deliverypreferred
Conduct cochlear surgeries, therapeutic delivery, cochlear dissections, tissue preparation, and phenotypic analyses in adult mice
from the posting - Auditory Brainstem Response (ABR) and DPOAE testingpreferred
Conduct functional hearing testing, including Auditory Brainstem Response (ABR) and Distortion Product Otoacoustic Emissions (DPOAE)
from the posting - Inner ear biology and hearing researchpreferred
Research experience in inner ear biology and hearing research
from the posting - Mouse models under IACUC protocolspreferred
Experience working with mouse models under IACUC-approved protocols
from the posting - Functional hearing assessmentpreferred
Experience performing functional hearing assessments, including ABR and DPOAE
from the posting - Hands-on cochlear injection techniquespreferred
Hands-on experience with cochlear injection techniques
from the posting - Experimental design and data analysispreferred
Demonstrated ability to design experiments, analyze data, and communicate scientific findings effectively
from the posting - Noise-induced, age-related, or ototoxicity-induced hearing loss modelsimplied
Experience with noise-induced, age-related, or ototoxicity-induced hearing loss models is desirable
from the posting
Read the full posting as the employer wrote it
Principal Investigator Dr. Volkan Ergin is seeking a Postdoctoral Fellow to join the Ergin Lab in the Department of Otolaryngology at Cedars-Sinai Medical Center.
Effective gene therapies require both efficient delivery vehicles and well-designed therapeutic cargos. The Ergin Lab addresses these challenges by engineering next-generation AAV vectors for targeted gene delivery to cochlear cell populations and developing innovative genetic cargo designs for inherited and acquired forms of hearing loss.
A substantial portion of this role involves hands-on animal research, including mouse models of acquired hearing loss, cochlear microsurgery, therapeutic delivery, and auditory functional testing. The position offers a unique opportunity to gain expertise across multiple disciplines, spanning gene therapy, synthetic biology, high-throughput screenings, and translational therapeutic development.
Dr. Ergin brings experience from both academia and industry, providing valuable mentorship for trainees interested in academic careers, industry positions, or entrepreneurial ventures. Postdoctoral fellows will be encouraged to pursue independent funding opportunities, including NIH K99/R00 awards and other career development mechanisms.
Primary Duties and Responsibilities
- May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
- May participate in publications and presentations as author or co-author.
- Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I.
- Analyzes, interprets, summarizes and compiles data.
Operates and maintains equipment and instruments
Qualifications
Education:
PhD, MD, MD/PhD, VMD, or equivalent doctoral degree in a relevant field.
Highly preferred experience:
Perform mouse breeding, colony management, husbandry, and experimental planning.
Conduct cochlear surgeries, therapeutic delivery, cochlear dissections, tissue preparation, and phenotypic analyses in adult mice.
Perform cochlear injection techniques in adult mice, including round window membrane (RWM) injection and canalostomy.
Conduct functional hearing testing, including Auditory Brainstem Response (ABR) and Distortion Product Otoacoustic Emissions (DPOAE).
Research experience in inner ear biology and hearing research
Experience working with mouse models under IACUC-approved protocols
Experience performing functional hearing assessments, including ABR and DPOAE
Hands-on experience with cochlear injection techniques
Demonstrated ability to design experiments, analyze data, and communicate scientific findings effectively.
Experience with noise-induced, age-related, or ototoxicity-induced hearing loss models is desirable.
Interested candidates should submit:
CV
A cover letter describing previous research experience, particularly in inner ear research, and outlining long-term career goals
The posting text is reproduced as the employer wrote it; the index adds nothing to it.